- Description Overview
- Directions for Use
- Ingredients
- Additional Resources
MTHFR Group Prenatal Methyl is a specifically formulated prenatal multivitamin suitable for both men and women. Prenatal Methyl is suitable for use in preconception, pregnancy and breastfeeding.
Unlike many other pregnancy multivitamins, Prenatal Methyl has been formulated folic acid-free and instead contains the biologically active form of folate 5-MTHF (levomefolic acid). This is the form that is easy for the body to use.
Prenatal Methyl is an ideal choice for:
- Preconception for men and women (ideal time is 3 months prior to pregnancy)
- Pregnancy
- During breastfeeding
- Vegans and vegetarians
- Those who find capsules easier to swallow than tablets
- May be used as a general multivitamin.
- Use in combination with our B12 and folate drops.
Package Size
90 Hard Capsules
Key Features
- Does not contain synthetic folic acid
- Contains the only biologically active form of folate, 5-MTHF (levomefolic acid)
- Easy-to-swallow capsules
- 5-MTHF supports the health of the growing baby during pregnancy
- 5-MTHF supports a healthy pregnancy by providing a source of folate that does not need to undergo enzymatic conversion before it can be utilised by the body
- Unisex formula suitable for both men and women
- Provides an ideal daily dose of 26 important nutrients for mother and baby including Vitamin B12, Iodine, Choline, CoQ10, Vitamin D, Calcium, Magnesium and zinc.
- Contains nutrients that support healthy reproduction
- Contains Vitamin B12 which is involved in DNA synthesis
- Contains zinc which plays a necessary role in the metabolism of reproductive hormones, skin health and immunity
- Contains iodine which is important for the brain and intellectual development of the baby
Free from
No added gluten, dairy, egg, fish/shellfish, GMO, nuts, sulphites, salicylates, yeast and sugar. Vegan friendly.
Adult Dose
Take 3 capsules once per day, with water, or as directed by your healthcare professional.
This product may be used in conjunction with Methyl Folate 100mcg Drops and Methyl B12 Drops
Children's Dose
This product is not recommended for children, please seek advice from a health professional regarding whether this product is suitable for children over 12.
Label Warnings
Advise your doctor of any medicine you take during pregnancy, particularly in your first trimester.
Do not take while on warfarin therapy without medical advice.
This medicine contains selenium which is toxic in high doses. A daily dose of 150 micrograms for adults of selenium from dietary supplements should not be exceeded.
Cautions & Contraindications
Do not take while on warfarin therapy without medical advice.
This medicine contains selenium which is toxic in high doses. A daily dose of 150 micrograms for adults of selenium from dietary supplements should not be exceeded.
Label Image

Excipients
Leucine, ascorbyl palmitate, colloidal anhydrous silica, vegetarian hard capsule (hypromellose and purified water).
Links to Relevant Blogs on Our Website
- Prenatal Folate and Homocysteine Affect Children’s IQs
- Risks of Folic Acid and Excessive Folate Intake in Pregnancy
- Folate or Folic?
- Folate and Brain
- Preconception, Pregnancy and Folate
- Role of 5-Methyletetrahydrofolate (5-MTHF) in Cardiovascular disease.
- B12 Deficiency and Folate
Links to Relevant Webinars
- The Best Place to Start if You Have Fertility Issues
- Folic Acid in Fertility
- Right Form & Dosage of Folate During Preconception
- Folate and MTHFR: Are They Affecting Your Pregnancy?
- Register for our FREE Advanced Fertility Webinar
Links to Relevant Research
- MTHFR Support. Folate or folic. MTHFR Support Australia. (Retrieved 2021).
- MTHFR Support. Folate and Brain. MTHFR Support Australia. (Retrieved 2021).
- MTHFR Support. Preconception, Pregnancy and Folate. MTHFR Support Australia. (Retrieved 2021).
- MTHFR Support. Role of 5-Methyletetrahydrofolate (5-MTHF) in Cardiovascular disease. MTHFR Support Australia. (Retrieved 2021).
- MTHFR Support. B12 deficiency and Folate. MTHFR Support Australia. (Retrieved 2021).
- MTHFR Support. Risks of Folic Acid and Excessive Folate Intake in Pregnancy. MTHFR Support Australia. (Retrieved 2021).
- Cochrane K, et al. Is natural (6S)-5-methyltetrahydrofolic acid as effective as synthetic folic acid in increasing serum and red blood cell folate concentrations during pregnancy? A proof-of-concept pilot study. Trials. 2020; 21(1), 380.
- Niederberger KE, et al. Safety evaluation of calcium L-methylfolate. Toxicol Rep. 2019; 6:1018-1030. Published 2019 Sep 26. doi:10.1016/j.toxrep.2019.09.012
- Servy EJ,et al. MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series. J Assist Reprod Genet. 2018;35(8):1431-1435. doi:10.1007/s10815-018-1225-2
- Vidmar Golja M, et al. Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate. J Clin Med. 2020;9(9):2836. Published 2020 Sep 2. doi:10.3390/jcm9092836
- Freeman MP, et al. A prenatal supplement with methylfolate for the treatment and prevention of depression in women trying to conceive and during pregnancy. Ann Clin Psychiatry. 2019 Feb;31(1):4-16. PMID: 30699214.
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Scaglione F, et al. Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica. 2014 May;44(5):480-8. doi: 10.3109/00498254.2013.845705. Epub 2014 Feb 4. PMID: 24494987.